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The management of ovarian cancer in pregnancy: a rare case report

  • Dewangga Wahyu Praja ,
  • Primandono Perbowo ,


Link of Video Abstract:


Introduction: Ovarian tumors are found in approximately 1 in 1000 pregnancies. The simultaneous management of three separate yet interconnected entities: the mother, the fetus, and the disease complicates cancer care during pregnancy. The treatment of a pregnant woman with ovarian cancer is described in this paper.

Case Presentation: A 24-year-old pregnant lady (G2P0A1, 24 weeks gestational age, [GA]) was brought to our hospital after a routine prenatal ultrasound revealed a 15x18 cm left adnexal tumor. We discovered the complex adnexal mass, which was approximately 20x13.3x16 cm in size, in the left ovary, producing severe bilateral hydronephrosis on magnetic resonance imaging (MRI). The laboratory tests performed were within normal limits except for higher serum lactate dehydrogenase levels. At 34 weeks GA, the pregnancy was terminated via cesarean section. The baby (female, 1,600 g) was born alive with no congenital defects and an Apgar score of 3-5-7. Following that, a unilateral salpingo-oophorectomy was performed.  Pathology indicated a high-grade serous carcinoma of the left ovary with positive ascites fluid but no evidence of metastases to the pelvic lymph nodes, omentum, or peritoneum (stage IC). We had planned to treat the woman with a paclitaxel-carboplatin combination, but she declined because she preferred to breastfeed her infant. She had no abdominal issues at 15 months and was still breastfeeding the baby.

Conclusion: Pregnancy-related epithelial ovarian cancer is uncommon but is a possibility. Clinical findings, diagnostic, and treatment strategies are roughly similar to non-pregnant patients, except for the timing of chemotherapy initiation. Further research is needed to give evidence regarding these mother-infant dyads' survival and health outcomes.


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How to Cite

Praja, D. W., & Primandono Perbowo. (2024). The management of ovarian cancer in pregnancy: a rare case report. Bali Medical Journal, 13(2), 610–613.




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