Antibacterial potential of Curcuma caesia Roxb ethanol extract against nosocomial infections

Siti Juariah; Fazleen Izzany Abu Bakar; Mohd Fadzelly Abu Bakar; Susi Endrini

doi:10.15562/bmj.v12i2.4320

Antibacterial potential of Curcuma caesia Roxb ethanol extract against nosocomial infections

Siti Juariah ,

Fazleen Izzany Abu Bakar ,

Mohd Fadzelly Abu Bakar ,

Susi Endrini ,

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DOI: https://doi.org/10.15562/bmj.v12i2.4320 |
Published: 2023-06-21

Abstract

Introduction: Nosocomial infection is one of the infections that occurs in the hospital environment and can cause several diseases, but nosocomial infection can also cause the sufferer to experience sepsis and even die if they do not get treatment. This study aims to determine the active compound of black turmeric extract (Curcuma caesia Roxb) and measure the inhibitory ability of several bacteria that cause nosocomial infections.

Methods: The diameter of the inhibitory zone was evaluated using the Kirby-Bauer disk diffusion method in this investigation

Results: The results showed that black turmeric extract has the potential to act as an antibacterial against both gram-positive and gram-negative bacteria. The highest results were obtained at the highest concentration (80%) against Staphylococcus aureus bacteria with a 15.10 ± 6.95 mm inhibition zone.

Conclusion: Based on the results of this study, it can be stated that black turmeric extract (Curcuma caesia Roxb) has the potential to be an antibacterial control for nosocomial infections.

References

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Ghashghaee A, Behzadifar M, Azari S, Farhadi Z, Luigi Bragazzi N, Behzadifar M, et al. Prevalence of nosocomial infections in Iran: A systematic review and meta-analysis. Med J Islam Repub Iran. 2018;32:48. doi: 10.14196/mjiri.32.48
Wuisan C, Rampengan SH, Korompis M. Factors related to the implementation of universal precautions by nurses in the inpatient unit ( IRINA F ) Prof . Dr . R . D . Kandou Central General Hospital Manado. 2017;6(1):68–72. doi: 10.15562/bmj.v6i1.458
Mssillou I, Agour A, Allali A, Saghrouchni H, Bourhia M, El Moussaoui A, et al. Antioxidant, Antimicrobial, and Insecticidal Properties of a Chemically Characterized Essential Oil from the Leaves of Dittrichia viscosa L. Molecules. 2022;27(7). doi: 10.3390/molecules27072282
Su T, Qiu Y, Hua X, Ye B, Luo H, Liu D, et al. Novel Opportunity to Reverse Antibiotic Resistance: To Explore Traditional Chinese Medicine With Potential Activity Against Antibiotics-Resistance Bacteria. Front Microbiol. 2020;11. doi: 10.3389/fmicb.2020.610070
Brandt KK, Amézquita A, Backhaus T, Boxall A, Coors A, Heberer T, et al. Ecotoxicological assessment of antibiotics: A call for improved consideration of microorganisms. Environ Int. 2015;85:189–205. doi: 10.1016/j.envint.2015.09.013
He K, Hain E, Timm A, Tarnowski M, Blaney L. Occurrence of antibiotics, estrogenic hormones, and UV-filters in water, sediment, and oyster tissue from the Chesapeake Bay. Sci Total Environ. 2019;650(Pt 2):3101–9. doi: 10.1016/j.scitotenv.2018.10.021
Homem V, Santos L. Degradation and removal methods of antibiotics from aqueous matrices--a review. J Environ Manage. 2011;92(10):2304–47. doi: 10.1016/j.jenvman.2011.05.023
Pandey D, Gupta A. ANTIBACTERIAL EFFICACY OF CURCUMA CAESIA FROM BASTAR DISTRICT OF CHHATTISGARH, INDIA. Int J Pharm Sci Res. 2014;5(6):2294–301. doi: 10.13040/IJPSR.0975-8232.5(6).2294-01
Jose S, Thomas TD. Comparative phytochemical and anti ‑ bacterial studies of two indigenous medicinal plants Curcuma caesia Roxb. International Journal of Green Pharmacy. 2014. doi: 10.4103/0973-8258.126828
Baghel SS, Baghel RS, Sharma K, Sikarwar I. Pharmacological activities of Curcuma caesia. Int J Green Pharm. 2013. doi: 10.4103/0973-8258.111590
Harborne J. Phytochemical methods – A Guide to Modern Technique of Plant analysis. London: Chapman and Hall; 1998.
Trease G, Evans W. Textbook of Pharmacognosy. 12th ed. London: Balliere, Tindall; 1983.
Taga MS, Miller EE, Pratt DE. Chia seeds as a source of natural lipid antioxidants. J Am Oil Chem Soc. 1984;61(5):928–31. Available from: https://doi.org/10.1007/BF02542169
Özkök A, D’arcy B, Sorkun K. Total Phenolic Acid and Total Flavonoid Content of Turkish Pine Honeydew. J ApiProduct ApiMedical Sci. 2010;2(2):65–71. doi: 10.3896/IBRA.4.02.2.01
Sarjono PR. Aktivitas Antibakteri Rimpang Temu Putih ( Curcuma mangga Vall ). J Sains Mat. 2007;15(2l):89–93.
Ariyanti NK, Darmayasa ida B gede, Sudirga saNg K. DAYA HAMBAT EKSTRAK KULIT DAUN LIDAH BUAYA (Aloe barbadensis Miller) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus ATCC 25923 DAN Escherichia coli ATCC 25922. J Biol. 2009;16(1):1–4.
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Fatoni AA, Alexandra FD, Triawanti. Streptococcuspyogenes DENGAN METODE CAKRAM KIRBY-BAUER Departemen Biokimia Fakultas Kedokteran Universitas Palangka Raya. J Kedokt Univ Palangka Raya. 2017;5(1):371–82.
Sudarmi K, Bagus I, Darmayasa G, Muksin IK. UJI FITOKIMIA DAN DAYA HAMBAT EKSTRAK DAUN JUWET ( Syzygium cumini ) TERHADAP PERTUMBUHAN Escherichia coli DAN Staphylococcus aureus ATCC PHYTOCHEMICAL AND INHIBITION OF JUWET LEAF EXTRACT ( Syzygium cumini ) ON GROWTH Escherichia coli AND Staphylococcus. J Simbiosis. 2017;5(2):47–51.
Riyanto EF, Nurjanah AN, Ismi SN. DAYA HAMBAT EKSTRAK ETANOL BUNGA TELANG ( Clitoria Ternatea Ervina Fauzia Riyanto , Ai Nuri Nurjanah , Sinta Nur Ismi , R . Suhartati Makanan dapat menjadi tempat hidup dan berkembang biak satu atau lebih jenis Beberapa dapat kerusakan pada makanan berasa. J Kesehat Bakti Tunas Husada. 2019;19(2):218–25.
Zaini WS, Banten PK. UJI DAYA HAMBAT EKSTRAK KEMBANG TELANG ( Clitoria ternatea ) TERHADAP PERTUMBUHAN BAKTERI Pseudomonas aeruginosa INHIBITORY TEST OF EGG FLOWER EXTRACT ( CLITORIA TERNATEA ) ON PSEUDOMONAS AERUGINOSA BACTERIA. Med (Media Inf Kesehatan). 2021;8(2):251–8.
Prayoga E. PERBANDINGAN EFEK EKSTRAK DAUN SIRIH HIJAU (Piper betle L.) DENGAN METODE DIFUSI DISK DAN SUMURAN TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus. Universitas Islam Negeri Syarif Hidayatullah; 2013.
Zeniusa P, Ramadhian MR, Nasution SH, Karima N, Kedokteran F, Lampung U. Uji Daya Hambat Ekstrak Etanol Teh Hijau Terhadap Escherichia coli Secara In Vitro THE INHIBITION TEST OF GREEN TEA ETHANOL EXTRACT ON Escherichia coli IN. Majorit. 2019;8(2):136–43.

[1] Tolera M, Abate D, Dheresa M, Marami D. Bacterial Nosocomial Infections and Antimicrobial Susceptibility Pattern among Patients Admitted at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Adv Med. 2018. doi: 10.1155/2018/2127814

[2] Ghashghaee A, Behzadifar M, Azari S, Farhadi Z, Luigi Bragazzi N, Behzadifar M, et al. Prevalence of nosocomial infections in Iran: A systematic review and meta-analysis. Med J Islam Repub Iran. 2018;32:48. doi: 10.14196/mjiri.32.48

[3] Wuisan C, Rampengan SH, Korompis M. Factors related to the implementation of universal precautions by nurses in the inpatient unit ( IRINA F ) Prof . Dr . R . D . Kandou Central General Hospital Manado. 2017;6(1):68–72. doi: 10.15562/bmj.v6i1.458

[4] Mssillou I, Agour A, Allali A, Saghrouchni H, Bourhia M, El Moussaoui A, et al. Antioxidant, Antimicrobial, and Insecticidal Properties of a Chemically Characterized Essential Oil from the Leaves of Dittrichia viscosa L. Molecules. 2022;27(7). doi: 10.3390/molecules27072282

[5] Su T, Qiu Y, Hua X, Ye B, Luo H, Liu D, et al. Novel Opportunity to Reverse Antibiotic Resistance: To Explore Traditional Chinese Medicine With Potential Activity Against Antibiotics-Resistance Bacteria. Front Microbiol. 2020;11. doi: 10.3389/fmicb.2020.610070

[6] Brandt KK, Amézquita A, Backhaus T, Boxall A, Coors A, Heberer T, et al. Ecotoxicological assessment of antibiotics: A call for improved consideration of microorganisms. Environ Int. 2015;85:189–205. doi: 10.1016/j.envint.2015.09.013

[7] He K, Hain E, Timm A, Tarnowski M, Blaney L. Occurrence of antibiotics, estrogenic hormones, and UV-filters in water, sediment, and oyster tissue from the Chesapeake Bay. Sci Total Environ. 2019;650(Pt 2):3101–9. doi: 10.1016/j.scitotenv.2018.10.021

[8] Homem V, Santos L. Degradation and removal methods of antibiotics from aqueous matrices--a review. J Environ Manage. 2011;92(10):2304–47. doi: 10.1016/j.jenvman.2011.05.023

[9] Pandey D, Gupta A. ANTIBACTERIAL EFFICACY OF CURCUMA CAESIA FROM BASTAR DISTRICT OF CHHATTISGARH, INDIA. Int J Pharm Sci Res. 2014;5(6):2294–301. doi: 10.13040/IJPSR.0975-8232.5(6).2294-01

[10] Jose S, Thomas TD. Comparative phytochemical and anti ‑ bacterial studies of two indigenous medicinal plants Curcuma caesia Roxb. International Journal of Green Pharmacy. 2014. doi: 10.4103/0973-8258.126828

[11] Baghel SS, Baghel RS, Sharma K, Sikarwar I. Pharmacological activities of Curcuma caesia. Int J Green Pharm. 2013. doi: 10.4103/0973-8258.111590

[12] Harborne J. Phytochemical methods – A Guide to Modern Technique of Plant analysis. London: Chapman and Hall; 1998.

[13] Trease G, Evans W. Textbook of Pharmacognosy. 12th ed. London: Balliere, Tindall; 1983.

[14] Taga MS, Miller EE, Pratt DE. Chia seeds as a source of natural lipid antioxidants. J Am Oil Chem Soc. 1984;61(5):928–31. Available from: https://doi.org/10.1007/BF02542169

[15] Özkök A, D’arcy B, Sorkun K. Total Phenolic Acid and Total Flavonoid Content of Turkish Pine Honeydew. J ApiProduct ApiMedical Sci. 2010;2(2):65–71. doi: 10.3896/IBRA.4.02.2.01

[16] Sarjono PR. Aktivitas Antibakteri Rimpang Temu Putih ( Curcuma mangga Vall ). J Sains Mat. 2007;15(2l):89–93.

[17] Ariyanti NK, Darmayasa ida B gede, Sudirga saNg K. DAYA HAMBAT EKSTRAK KULIT DAUN LIDAH BUAYA (Aloe barbadensis Miller) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus ATCC 25923 DAN Escherichia coli ATCC 25922. J Biol. 2009;16(1):1–4.

[18] Asdedi DJ, Arifian H, Rijai L. UJI AKTIVITAS ANTIBAKTERI EKSTRAK RIMPANG KUNYIT HITAM (CURCUMA CAESIA ROXB. ). Pros Semin Nas Kefarmasian Ke-4. 2016;59–65.

[19] Fatoni AA, Alexandra FD, Triawanti. Streptococcuspyogenes DENGAN METODE CAKRAM KIRBY-BAUER Departemen Biokimia Fakultas Kedokteran Universitas Palangka Raya. J Kedokt Univ Palangka Raya. 2017;5(1):371–82.

[20] Sudarmi K, Bagus I, Darmayasa G, Muksin IK. UJI FITOKIMIA DAN DAYA HAMBAT EKSTRAK DAUN JUWET ( Syzygium cumini ) TERHADAP PERTUMBUHAN Escherichia coli DAN Staphylococcus aureus ATCC PHYTOCHEMICAL AND INHIBITION OF JUWET LEAF EXTRACT ( Syzygium cumini ) ON GROWTH Escherichia coli AND Staphylococcus. J Simbiosis. 2017;5(2):47–51.

[21] Riyanto EF, Nurjanah AN, Ismi SN. DAYA HAMBAT EKSTRAK ETANOL BUNGA TELANG ( Clitoria Ternatea Ervina Fauzia Riyanto , Ai Nuri Nurjanah , Sinta Nur Ismi , R . Suhartati Makanan dapat menjadi tempat hidup dan berkembang biak satu atau lebih jenis Beberapa dapat kerusakan pada makanan berasa. J Kesehat Bakti Tunas Husada. 2019;19(2):218–25.

[22] Zaini WS, Banten PK. UJI DAYA HAMBAT EKSTRAK KEMBANG TELANG ( Clitoria ternatea ) TERHADAP PERTUMBUHAN BAKTERI Pseudomonas aeruginosa INHIBITORY TEST OF EGG FLOWER EXTRACT ( CLITORIA TERNATEA ) ON PSEUDOMONAS AERUGINOSA BACTERIA. Med (Media Inf Kesehatan). 2021;8(2):251–8.

[23] Prayoga E. PERBANDINGAN EFEK EKSTRAK DAUN SIRIH HIJAU (Piper betle L.) DENGAN METODE DIFUSI DISK DAN SUMURAN TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus. Universitas Islam Negeri Syarif Hidayatullah; 2013.

[24] Zeniusa P, Ramadhian MR, Nasution SH, Karima N, Kedokteran F, Lampung U. Uji Daya Hambat Ekstrak Etanol Teh Hijau Terhadap Escherichia coli Secara In Vitro THE INHIBITION TEST OF GREEN TEA ETHANOL EXTRACT ON Escherichia coli IN. Majorit. 2019;8(2):136–43.

Antibacterial potential of Curcuma caesia Roxb ethanol extract against nosocomial infections

Abstract

References

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