Skip to main content Skip to main navigation menu Skip to site footer

Cardiac myxoma misdiagnose as infective endocarditis in a patient with acute limb ischemia and cardioembolic cerebral stroke: a case report

  • Putri Oktaviani Zulfa ,
  • Yopie Afriandi Habibie ,

Abstract

Introduction: Fever, systemic embolism, and intra-cardiac masses are all symptoms of Infective Endocarditis (IE) and Cardiac Myxoma (CM)1. As a result, despite proper imaging studies, these diseases are frequently misdiagnosed one for the other.2

Case description: A 23-years-old female patient was admitted to emergency department of Zainoel Abidin General Hospital with acute onset right lower extremity pain for the last few hours and presented roth spots of the retina. The next day after admission, she presented fever. The patient denied having chronic disease, drug abuse, and thrombotic history. Tooth decay were found. Transthoracic Echocardiography (TTE) were obtained due to concern of infective endocarditis. Head CT-scan revealed cardioembolic cerebral stroke. TTE showed ejection fraction 56%, severe mitral regurgitation, and a mobile mass size 3.1x2.4 cm in mitral valve, attached to anterior mitral leaflet. The patient underwent thrombectomy, stroke therapy, dental tooth decay treatment, and lower limb rehabilitation at that moment, before having Mitral Valve Replacement (MVR) surgery. Six months afterward MVR surgery was done, rather than vegetation, we found a 50cc cardiac myxoma in anterior mitral valve leaflet. A 27mm bioprosthetic valve was installed. The patient was recovered quickly and she was able to discharge from hospital in the next 7 days after procedure without any further issue.

Conclusion: In order to effectively manage the patients, it is crucial to distinguish between IE and cardiac myxoma. The mainstay of treatment for cardiac myxoma cases is surgery, which has an excellent prognosis. To evaluate for recurrence, long-term follow-up is frequently required.

References

  1. Fitzgerald GP, Coughlan JJ, Satti Z, Arnous S. Atrial myxoma presenting as infective endocarditis. BMJ Case Rep. 2018;2018:bcr2017223656. Available from: https://pubmed.ncbi.nlm.nih.gov/29525758
  2. Kim CH, Je HG, Ju MH, Lee C-H. Cardiac myxoma misdiagnosed as infective endocarditis: a case of Carney complex. J Cardiothorac Surg. 2020;15(1):188. Available from: https://pubmed.ncbi.nlm.nih.gov/32711545
  3. Daoud N, Malikayil K, Regalla D, Alam M. An unusual case of infective endocarditis with acute limb ischemia and cardiac embolism. IDCases. 2021;25:e01201–e01201. Available from: https://pubmed.ncbi.nlm.nih.gov/34189046
  4. Aiello VD, de Campos FPF. Cardiac Myxoma. Autops case reports. 2016;6(2):5–7. Available from: https://pubmed.ncbi.nlm.nih.gov/27547737
  5. Kawabori M, Benkert AR, Warner KG, Patel AR, Arkun K, Chen FY, et al. Uncommon Cause of Fever and Embolism: Staphylococcus epidermidis Infected Myxoma. Ann Thorac Surg. 2019;107(4):e283. Available from: http://dx.doi.org/10.1016/j.athoracsur.2018.09.070
  6. Van Schil P. Faculty Opinions recommendation of The 2015 world health organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. [Internet]. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature. Faculty Opinions Ltd; 2017. Available from: http://dx.doi.org/10.3410/f.725757738.793528485
  7. Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JHM, Beasley MB, et al. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol. 2015;10(9):1243–60. Available from: https://pubmed.ncbi.nlm.nih.gov/26291008/
  8. Griborio-Guzman AG, Aseyev OI, Shah H, Sadreddini M. Cardiac myxomas: clinical presentation, diagnosis and management. Heart. 2021;108(11):827–33. Available from: http://dx.doi.org/10.1136/heartjnl-2021-319479
  9. Rafi Khourgami M, Ershad A, Mozaffari K. Left Atrial Myxoma Misdiagnosis as Infective Endocarditis: A Case Report. Arch Pediatr Infect Dis. 2020;9(3). Available from: http://dx.doi.org/10.5812/pedinfect.108029
  10. Aiello VD, Campos FPF. Cardiac Myxoma. Autopsy and Case Reports. 2016;6(2):5-7. Available from: https://doi.org/10.4322/acr.2016.030

How to Cite

Zulfa, P. O. ., & Habibie, Y. A. (2023). Cardiac myxoma misdiagnose as infective endocarditis in a patient with acute limb ischemia and cardioembolic cerebral stroke: a case report . Bali Medical Journal, 12(1), 184–186. https://doi.org/10.15562/bmj.v12i1.3963

HTML
4

Total
1

Share

Search Panel

Putri Oktaviani Zulfa
Google Scholar
Pubmed
BMJ Journal


Yopie Afriandi Habibie
Google Scholar
Pubmed
BMJ Journal