Background. Severe acute malnutrition (SAM) is one of major cause of morbidity and mortality in children, especially under 5 years old. Successful management of SAM can be determined by many factors. Therefore, the purpose of this study was to identify the factors associated with outcome of inpatient SAM management.
Methods. The present study performed a cohort study on children with SAM admitted to dr. Mohammad Hosein Hospital Palembang (RSMH) from January to July 2021. Outcome was weight gain during 14 days of observation period and rehabilitation phase, defined in g/kg body weight (BW)/day, and was categorized as follows: poor (<5 g/kg BW/day) and moderate-good (≥5 g/kg BW/day).
Results. There were 87 children, 62% were female, and median age was 14 (1-60) months old. Moderate-good outcome was found in 31 subjects (36%) with weight gain during rehabilitation phase was 2.10 (0–71.4) g/kg BW/day. The highest mean weight gain was in subjects aged 6-<12 months which was 7.68.2 g/kg BW/day. Most subjects had good acceptability with median 100% (44.4-100%) (p=0.696), while 36% showed diet intolerance such as vomiting (24%) and diarrhea (17%) (p=0.656). Most common associated symptom was shortness of breath (32%) (p=0.066). Non-infectious was more common than infectious disease (47% vs 44%) with p=0.470 and p=0,110, respectively. All of subjects with tuberculosis showed poor outcome (RR 1.70; 95% CI 1.41-2.06; p=0.004).
Conclusion. In this study, SAM treatment outcome was not influenced by associated symptoms, accompanying disease, diet intolerance, and acceptability. However, tuberculosis in SAM patients significantly raised the poor outcome.