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CRP Levels, Thrombocyte Index and Coagulation Status with TEG Profile in ITP Patients

  • Suryanto Suryanto ,
  • Banundari Racmawati ,
  • Imam Budiwiyono ,


Abstract

Examinations related to Immune Thrombocytopenia (ITP) cases have been widely demonstrated in diagnosing and monitoring hemostasis status. The increased MPV and PDW have a high sensitivity to the diagnosis of ITP and CRP is one of the causes of ITP. Monitoring of bleeding in ITP still uses conventional examination. Thromboelastography (TEG) is a global hemostasis assessment tool that assesses real-time overall hemostasis. TEG profiles especially MA and R-time can be used for case assessment of ITP patients. This research describes the correlation between CRP levels, platelet index and coagulation status with TEG profiles (MA and R-time) in ITP patients. This research used analytical observational with cross sectional approach. A sample of 32 respondents aged >18 years with a platelet count <150,000/mm3. Then the respondents measured EDTA blood samples for platelet index (MPV and PDW) and CRP levels, in the citrate blood sample 3.2% measured coagulation status (aPTT and PT) as well as examining the TEG profile, especially R-time and MA. Correlation test uses the Pearson test for data that is normally distributed, while the Spearman test is for data that are not normally distributed. There is a correlation between CRP levels, platelet counts, MPV and MA TEG (p=0.002, p=0.000, p=0.001), there is no correlation between PDW and MA TEG (p=0.06), there is a correlation between aPTT and R-time TEG (p=0.001) and there is no correlation between PT and R-time TEG (p=0.667). Overall, there is a correlation between conventional variables and the TEG profile in ITP patients.

Keywords: ITP CRP TEG

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How to Cite

Suryanto, S., Racmawati, B., & Budiwiyono, I. (2021). CRP Levels, Thrombocyte Index and Coagulation Status with TEG Profile in ITP Patients. Bali Medical Journal, 10(3), 1347–1353. https://doi.org/10.15562/bmj.v10i3.2973
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Suryanto Suryanto
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Banundari Racmawati
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Imam Budiwiyono
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