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Correlation between Bone Mineral Density (BMD) with blood phosphorus levels in elderly women: study using Dual Energy X-ray Absorptiometry (DXA)

  • Adhikarmika Aripriandari ,
  • Hermina Sukmaningtyas ,
  • Dwi Ngestiningsih ,
  • Lusiana Batubara ,

Abstract

Background: The main constituent of Bone Mineral Density (BMD) is bone mineral, with the main composition of the hydroxyapatite complex, a combination of calcium and phosphorus. In the aging process, the mineral content in the bones will decrease, resulting in lower BMD than normal levels (osteopenia) or leading to the most common musculoskeletal disorder as well as morbidity in the elderly population. This study aims to determine the correlation between BMD and blood phosphorus levels in elderly women.

Methods: This cross-sectional study was based on data from several geriatric health centers in Semarang from March until June 2019. There were 29 female respondents aged ? 60 years who participated and signed informed consent of this study. The study performed laboratory tests to assess blood phosphorus levels and BMD examination with Dual Energy X-ray Absorption (DXA). BMD is categorized based on World Health Organization (WHO) criteria into normal, osteopenia, and osteoporosis categories. Data were analyzed using SPSS version 17 for Windows.

Results: Most of the subjects were 60-69 years old group (69.0%), followed by osteoporosis in the BMD category (62.0%) and normal blood phosphorus levels (83.0%). There was no significant correlation between BMD and blood phosphorus levels (p> 0.05), but there was a tendency for a negative correlation between BMD and blood phosphorus levels (r=-0.096).

Conclusion: The result shows no correlation between blood phosphorus level and BMD. 

References

  1. Salehi-Abari I. Early diagnosis of osteopenia/osteoporosis by bone mineral density test using DXA method in early adulthood-a pre-emptive step towards future bone health. Int J Rheum Dis. 2017;20(1):122-125.
  2. Sutlovic D, Boric I, Sliskovic L, Popovic M, Knezovic Z, Nikolic I, et al. Bone mineral density of skeletal remains: Discordant results between chemical analysis and DXA method. Leg Med (Tokyo). 2016;20:18-22.
  3. Parameshwari S, Mohankumar JB. A Comparative Study on Serum Mean Calcium, Phosphorus Levels and Berevages Intake, and Osteoporosis in Selected Post-Menopausal Women of Thanjavur District. Heal Sci An Int J. 2015;5(2):1-6
  4. Briot K. DXA parameters: beyond bone mineral density. Joint Bone Spine. 2013;80(3):265-269.
  5. Sheu A, Diamond T. Bone mineral density: testing for osteoporosis. Aust Prescr. 2016;39(2):35-39.
  6. Tai V, Leung W, Grey A, Reid IR, Bolland MJ. Calcium intake and bone mineral density: systematic review and meta-analysis. BMJ. 2015;351:h4183.
  7. Anderson JJB, Adatorwovor R, Roggenkamp K, Suchindran CM. Lack of Influence of Calcium/Phosphorus Ratio on Hip and Lumbar Bone Mineral Density in Older Americans: NHANES 2005-2006 Cross-Sectional Data. J Endocr Soc. 2017;1(5):407-414.
  8. Geusens PP, Boonen S. Osteoporosis and the growth hormone-insulin-like growth factor axis. Horm Res. 2002;58 Suppl 3:49-55.
  9. Ali NK. Evaluation of the Main Minerals in Osteoporosis Patients : Calcium , Phosphorus , Vitamin 25 (OH) D and Alkaline Phosphatase as a Case Study. Indian Journal of Public Health Research & Development. 2019;10(6):583-587.
  10. Shakoor S, Ilyas F, Abbas N, Mirza MA, Arif S. Prevalence of Osteoporosis in Relation To Serum Calcium and Phosphorus in Aging Women. J Glob Innov Agric Soc Sci. 2015;2(2):70-75.
  11. Peacock M. Phosphate Metabolism in Health and Disease. Calcif Tissue Int. 2021;108(1):3-15.
  12. Balani S, Perwad F. Fibroblast growth factor 23 and phosphate homeostasis. Curr Opin Nephrol Hypertens. 2019;28(5):465-473.
  13. Manghat P, Sodi R, Swaminathan R. Phosphate homeostasis and disorders. Ann Clin Biochem. 2014;51(Pt 6):631-656.
  14. Clarke BL, Vokes TJ, Bilezikian JP, Shoback DM, Lagast H, Mannstadt M. Effects of parathyroid hormone rhPTH(1-84) on phosphate homeostasis and vitamin D metabolism in hypoparathyroidism: REPLACE phase 3 study. Endocrine. 2017;55(1):273-282.

How to Cite

Aripriandari, A., Sukmaningtyas, H., Ngestiningsih, D., & Batubara, L. (2021). Correlation between Bone Mineral Density (BMD) with blood phosphorus levels in elderly women: study using Dual Energy X-ray Absorptiometry (DXA). Bali Medical Journal, 10(3), 1002–1005. https://doi.org/10.15562/bmj.v10i3.2848

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Adhikarmika Aripriandari
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Hermina Sukmaningtyas
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Dwi Ngestiningsih
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Lusiana Batubara
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