Nursing students should have some competencies to be professional nurses, like creativity, the ability to think critically, and have good communication and collaboration skills. We change the traditional learning approach to a student-centered approach to improve critical thinking skills. Some studies implement the SCL methods and we need to know the role of SCL learning strategies in improving critical thinking skills. This literature review aims to analyze the role of the student-centered learning application in improving critical thinking skills in health profession students. The design used literature review with the articles reviewed is the result of original research selected based on inclusion and exclusion criteria using a database with electronic searches on Pubmed, Science Direct, Proquest, Sage Journal, and Google Scholar, published in 2016 - 2021 which contains teaching methods that can increase the health profession student’s critical thinking skills. Search strategies with keywords and terms used in English are health profession student, student center learning, and critical thinking. The various learning methods used to improve the critical thinking of health profession students were case-based learning method, simulation learning method, cooperative learning method, problem-based learning method, team-based learning method, self-directed learning method, experiential learning method, and debate and role-play learning methods. All teaching methods are influential in increasing critical thinking in health profession students.