Objective: Cells and tissues are continuously damaged by reactive oxygen species. Cigarette smokeÂ is one of an exogenous source of free radical containing more than 4000 chemical compounds, thatÂ triggering the formation of free radicals related to diseases and aging process. Anthocyanins areÂ potent antioxidants that are widely distributed in fruit, vegetables, red wines and Ipomea batatas. TheÂ aim of this study was to determine the effect of Ipomea batatas as a source of antioxidants inÂ decreasing levels of alondialdehyde (MDA) and increasing of Nitrous oxide (nitrite/nitrate/NOx)
plasma in moderate smokers of workers at Denpasar.
Method: This was an experimental study with aÂ pretest-posttest control groups design. There are 33 moderate smokers who were divided into threeÂ groups, control group (placebo), treatment group with 15 ml purple sweet potato syrup (P1) and 30 mlÂ (P2), for 14 days. All groups were performed the laboratory examinations for MDA and NOx plasmaÂ before and after the treatment.
Results: This study showed that there were significant differences (p<0.05) both in MDA and NOx plasma levels in the control group, P1 and P2. The decrease of MDA
levels on P1 was 35.39% and on P2 was 49.87%. The increase of NOx plasma levels was 7.78% forÂ P1 and 14.68% for P2.
Conclusion: From this study, it can be concluded that Ipomea batatas syrupÂ contains of 8mg/mL anthocyanins, probably play a role in reducing the free radical and thus reducing
the risk of disease and slowing the aging process.