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Association between clinical parameter, laboratorium and radiology along with validation of scoring system with lung tuberculosis status in adult HIV patients

  • Wayan Evie Frida Yustin ,
  • I Ketut Agus Somia ,
  • Ni Luh Putu Eka Arisanti ,
  • I G N Bagus Ngurah Artana ,
  • Ida Ayu Jasminarti Dwi Kusumawardani ,
  • Ni Wayan Candrawati ,
  • Ida Bagus Ngurah Rai ,


Background: Many obstacles are commonly found in diagnosing tuberculosis in HIV patients, increasing the risk of morbidity and mortality in patients. This study aimed to assess the association of several clinical, laboratory and radiological parameters to pulmonary TB status in adult HIV patients.

Method: This was an observational analytic study with cross-sectional design conducted in Bali from January to June 2021, involved patients with HIV. Bivariate analysis was performed with chi-square, while multivariate analysis with multiple logistic regression. The adjusted odds ratio indicates the association of each parameter with pulmonary TB status and used as the base to compile a score for adult TB.

Results : From 105 subjects, 92 subjects met the research requirements. The results of the multivariate analysis obtained several significant variables (p < 0.05); cough (OR: 17.0), shortness of breath (OR: 21.0), fever (OR: 20,0), weight loss (OR: 5.5), night sweats (OR: 31.6), chest radiograph (OR: 80.0), geneXpert (OR: 27.8), neutrophils (OR: 6.2), NLR (OR: 10.7), MLR (OR: 11.3) and ESR (OR: 11.9). The results of pulmonary TB scoring in adult HIV patients with a value of > 55 indicate pulmonary TB and < 55 non-pulmonary TB with a significant validity test result (p-value < 0.001).

Conclusion: Clinical, laboratory and radiological parameters have a significant relationship with TB status in adult HIV patients and can be used as complements to the gold standard if the results of the XpertMtb examination are doubtful or not in accordance with the patient's clinical course. 


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How to Cite

Yustin, W. E. F., Somia, I. K. A., Arisanti, N. L. P. E., Artana, I. G. N. B. N., Kusumawardani, I. A. J. D., Candrawati, N. W., & Rai, I. B. N. (2021). Association between clinical parameter, laboratorium and radiology along with validation of scoring system with lung tuberculosis status in adult HIV patients. Bali Medical Journal, 10(3), 1085–1092.




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Wayan Evie Frida Yustin
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I Ketut Agus Somia
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Ni Luh Putu Eka Arisanti
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I G N Bagus Ngurah Artana
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Ida Ayu Jasminarti Dwi Kusumawardani
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Ni Wayan Candrawati
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Ida Bagus Ngurah Rai
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