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The molecular mechanisms of secondary osteoporosis: a literature review


Osteoporosis is a metabolic bone disorder characterized by low bone mass, microstructural degradation, decreased bone mineral density, and compromised bone strength. It is known as a disorder affecting the older population. However, aging is not the only factor involved. Millions of people with osteoporosis remain undiagnosed and often involve secondary causes. In some studies, it is estimated that approximately 20-30% of postmenopausal women and above 50% of men having secondary osteoporosis. Secondary osteoporosis usually showed no clear clinical manifestations, and thus allow its progression to a fracture. The process of osteoporosis is complex as it involves various factors. This article tries to provide an in-depth review of the problem regarding the mechanisms of secondary osteoporosis and the significance of related risk factors. At the same time, it emphasized the molecular mechanisms of osteoporosis


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How to Cite

Hajiyev, A., Azizova, G., & Efendiyev, A. (2020). The molecular mechanisms of secondary osteoporosis: a literature review. Bali Medical Journal, 9(2), 562–566.




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