Duration of chronic kidney disease: as predisposition factor for erectile dysfunction in routine hemodialysis patients

Jufriady Ismy; Muhammad Iqbal; Dahril Dahril

doi:10.15562/bmj.v9i1.1735

Duration of chronic kidney disease: as predisposition factor for erectile dysfunction in routine hemodialysis patients

Jufriady Ismy ,

Muhammad Iqbal ,

Dahril Dahril ,

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DOI: https://doi.org/10.15562/bmj.v9i1.1735 |
Published: 2020-04-01

Abstract

Background: Chronic kidney disease (CKD) has a high global prevalence with an estimated prevalence of 10.6%. While the global prevalence of erectile dysfunction (ED) is 18.4% in men aged> 20 years and 33% aged> 50 years. ED is found in 70% of CKD patients. The aim of the study is to determine the relationship between duration of chronic kidney disease with ED in patients undergoing routine hemodialysis.

Method: A cross-sectional study conducted from 1 October 2018 to 18 June 2019 of 60 CKD patients undergoing hemodialysis. History and examination were carried out using the International Erectile Function Index (IIEF-5) questionnaire.

Result: Out of 60 samples, 42 patients (70%) had ED. The average duration of chronic kidney disease resulting in mild, moderate-moderate and moderate ED was 10.94 Â± 10.79, 24.20 Â± 17.84 and 38.40 Â± 16.78 months, respectively. Univariate analysis using Spearman rank correlation showed a direct relationship between the duration of CKD and DE (P = 0.00, R squared 0.814).

Conclusion: Duration of chronic kidney disease has strong relationship with ED in hemodialysis patients

References

Murphree DD, Thelen SM. Chronic kidney disease in primary care. The Journal of the American Board of Family Medicine. 2010;23(4):542-50.
Watnick S, Dirkx TC. Kidney Disease. In: Papadakis MA, McPhee SJ, Rabow MW, editors. Current Medical Diagnosis & Treatment 2017. New York, NY: McGraw-Hill Education; 2016.
Levey AS, Coresh J. Chronic kidney disease. The Lancet.379(9811):165-80.
Warhamna N, Husna C. Chronic kidney disease based on duration of haemodyalisis in Dr. Zainoel Abidin General Hospital Banda Aceh. Nursery Journal. 2016;1(1):1-6.
Indonesia KKR.Current situation of chronic kidney disease in Indonesia; 2017.
Palmer BF. Sexual dysfunction in men and women with chronic kidney disease and end-stage kidney disease. Advances In Renal Replacement Therapy. 2003;10(1):48-60.
Mesquita JFP, Ramos TF, Mesquita FP, Netto JMB, Bastos MG, de Figueiredo AA. Prevalence of erectile dysfunction in chronic renal disease patients on conservative treatment. Clinics. 2012;67(2):181-3.
Wincze JP, Weisberg RB. Sexual dysfunction: A guide for assessment and treatment: Guilford Publications; 2015.
Shamloul R, Ghanem H. Erectile dysfunction. The Lancet. 2013;381(9861):153-65.
Al Khallaf HH. Analysis of sexual functions in male nondiabetic hemodialysis patients and renal transplant recipients. Transplant International. 2010;23(2):176-81.
Collins AJ, Foley RN, Gilbertson DT, Chen S-C. United States Renal Data System public health surveillance of chronic kidney disease and end-stage renal disease. Kidney International Supplements. 2015;5(1):1-7.
Delles C, Vanholder R. Chronic kidney disease. Clin Sci. 2017;131(3):225-6.
Papadopoulou E, Varouktsi A, Lazaridis A, Boutari C, Doumas M. Erectile dysfunction in chronic kidney disease: From pathophysiology to management. World Journal Of Nephrology. 2015;4(3):379-386.
Rathi M, Ramachandran R. Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology. Indian Journal of Endocrinology and Metabolism. 2012;16(2):214-9.
Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. The Lancet. 2012;89(10075):1238-52.
Eknoyan G, Lameire N, Eckardt K, Kasiske B, Wheeler D, Levin A, et al. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2013;3(1):5-14.
Murphree DD, Thelen SM. Chronic Kidney Disease in Primary Care. The Journal of the American Board of Family Medicine. 2010;23(4):542.
Gorsane I, Amri N, Younsi F, Helal I, Kheder A. Erectile dysfunction in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2016;27(1):23-8.
Mesquita JFP, Ramos TF, Mesquita FP, Bastos Netto JM, Bastos MG, Figueiredo AAd. Prevalence of erectile dysfunction in chronic renal disease patients on conservative treatment. Clinics (Sao Paulo, Brazil). 2012;67(2):181-3.
Shen Y-C, Weng S-F, Wang J-J, Tien K-J. Erectile Dysfunction and Risk of End-Stage Renal Disease Requiring Dialysis: A Nationwide Population-Based Study. PLOS ONE. 2014;9(7):e102055.

[1] Murphree DD, Thelen SM. Chronic kidney disease in primary care. The Journal of the American Board of Family Medicine. 2010;23(4):542-50.

[2] Watnick S, Dirkx TC. Kidney Disease. In: Papadakis MA, McPhee SJ, Rabow MW, editors. Current Medical Diagnosis & Treatment 2017. New York, NY: McGraw-Hill Education; 2016.

[3] Levey AS, Coresh J. Chronic kidney disease. The Lancet.379(9811):165-80.

[4] Warhamna N, Husna C. Chronic kidney disease based on duration of haemodyalisis in Dr. Zainoel Abidin General Hospital Banda Aceh. Nursery Journal. 2016;1(1):1-6.

[5] Indonesia KKR.Current situation of chronic kidney disease in Indonesia; 2017.

[6] Palmer BF. Sexual dysfunction in men and women with chronic kidney disease and end-stage kidney disease. Advances In Renal Replacement Therapy. 2003;10(1):48-60.

[7] Mesquita JFP, Ramos TF, Mesquita FP, Netto JMB, Bastos MG, de Figueiredo AA. Prevalence of erectile dysfunction in chronic renal disease patients on conservative treatment. Clinics. 2012;67(2):181-3.

[8] Wincze JP, Weisberg RB. Sexual dysfunction: A guide for assessment and treatment: Guilford Publications; 2015.

[9] Shamloul R, Ghanem H. Erectile dysfunction. The Lancet. 2013;381(9861):153-65.

[10] Al Khallaf HH. Analysis of sexual functions in male nondiabetic hemodialysis patients and renal transplant recipients. Transplant International. 2010;23(2):176-81.

[11] Collins AJ, Foley RN, Gilbertson DT, Chen S-C. United States Renal Data System public health surveillance of chronic kidney disease and end-stage renal disease. Kidney International Supplements. 2015;5(1):1-7.

[12] Delles C, Vanholder R. Chronic kidney disease. Clin Sci. 2017;131(3):225-6.

[13] Papadopoulou E, Varouktsi A, Lazaridis A, Boutari C, Doumas M. Erectile dysfunction in chronic kidney disease: From pathophysiology to management. World Journal Of Nephrology. 2015;4(3):379-386.

[14] Rathi M, Ramachandran R. Sexual and gonadal dysfunction in chronic kidney disease: Pathophysiology. Indian Journal of Endocrinology and Metabolism. 2012;16(2):214-9.

[15] Webster AC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. The Lancet. 2012;89(10075):1238-52.

[16] Eknoyan G, Lameire N, Eckardt K, Kasiske B, Wheeler D, Levin A, et al. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2013;3(1):5-14.

[17] Murphree DD, Thelen SM. Chronic Kidney Disease in Primary Care. The Journal of the American Board of Family Medicine. 2010;23(4):542.

[18] Gorsane I, Amri N, Younsi F, Helal I, Kheder A. Erectile dysfunction in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2016;27(1):23-8.

[19] Mesquita JFP, Ramos TF, Mesquita FP, Bastos Netto JM, Bastos MG, Figueiredo AAd. Prevalence of erectile dysfunction in chronic renal disease patients on conservative treatment. Clinics (Sao Paulo, Brazil). 2012;67(2):181-3.

[20] Shen Y-C, Weng S-F, Wang J-J, Tien K-J. Erectile Dysfunction and Risk of End-Stage Renal Disease Requiring Dialysis: A Nationwide Population-Based Study. PLOS ONE. 2014;9(7):e102055.

Duration of chronic kidney disease: as predisposition factor for erectile dysfunction in routine hemodialysis patients

Abstract

References

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