Relationship of albumin serum levels and Neutrophil-Lymphocyte Ratios (NLR) on activities of daily living elderly patients with delirium at Sanglah General Hospital, Bali, Indonesia

I Made Arya Winangun; I Gusti Putu Suka Aryana; I Nyoman Astika; Raden Ayu Tuty Kuswardhani

doi:10.15562/bmj.v9i1.1639

Relationship of albumin serum levels and Neutrophil-Lymphocyte Ratios (NLR) on activities of daily living elderly patients with delirium at Sanglah General Hospital, Bali, Indonesia

I Made Arya Winangun ,

I Gusti Putu Suka Aryana ,

I Nyoman Astika ,

Raden Ayu Tuty Kuswardhani ,

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DOI: https://doi.org/10.15562/bmj.v9i1.1639 |
Published: 2020-04-01

Abstract

Background: Delirium often occurs to the elderly, which is associated with inflammation, malnutrition and low activities of daily living (ADL). The reduced ADL is associated with poor outcomes and death. ADL is affected by malnutrition and inflammation. Albumin is a marker for malnutrition and inflammation, while the neutrophil-lymphocyte ratio (NLR) is a marker for inflammation. This study aims to determine the relationship between albumin serum levels and NLR to ADL in elderly delirium patients in Sanglah Hospital Denpasar.Methods: A cross-sectional correlative study among elderly delirium patients were conducted at Sanglah Hospital Denpasar from January to July 2018. The variables studied were albumin levels, NLR and ADL scores. Data analysis using SPSS version 23 with Pearson or Spearman correlation tests to determine the relationship between the variables examined.Results: Total of 73 patients were sampled. The average albumin levels were 3.35 gram/dL, the median NLR was 8.17 and the median ADL scores were 3. There was no significant relationship between albumin and ADL in elderly delirium patients (p=0.35, r=0.10), but a significant correlation was obtained between NLR and ADL scores (p=0.04, r=-0.24).Conclusion: Albumin did not significantly affect ADL. NLR was negatively correlated with ADL. The higher the NLR, the lower the ADL of elderly delirium patients.

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