Background: Normalities of the cervix-epithelial-cells (CEC) can be determined base on the cell morphology and their nucleus. If one of the cervix-epithelial-cells has gene mutations, it will form mutant clones, further growing, developing and malignant. The Fas-promoter-670 gene is allegedly associated with cervical cancer.
Case Presentation: A Â 30-year-old Â of high-risk Indonesian mother, Â has two children, on April 21th Â 2016 has followed Pap smear examination with thin prep method. Subjects, in this case, had normal cervix-epithelial-cells. Characteristics of the cervix-epithelial-cells include cell biometrics among others cell length, cell width, cell area, cell perimeter, nucleus area, and nucleus perimeter. Fas-promoter-670 genotype in the lymphocytes-cells is AA (normal= wild type), whereas in the cervix-epithelial-cells is GA (heterozygous mutant).
Conclusion: Based on characteristic of cell biometrics, cervix-epithelial-cells in high-risk Indonesian mother is normal. The genotype of the Fas-promoter-670 gene in the lymphocyte cells is AA, whereas in the cervix-epithelial-cells has mutation to GA.