Background: Osteoporosis is a systemic disease and involves all bones, including temporal bone. Demineralization of temporal bone including otic capsule and auditory ossicles is suspected to be the cause of hearing loss.
Purpose: This study aims to determine whether osteoporosis can cause the decrease of otic capsule and auditory ossicles density and increase the hearing threshold.
Method: an Observational analytic study with a cross sectional design involving 18 osteoporosis patients and 18 non-osteoporosis patients who had bone mineral density examination. The hearing was examined with Interaccoustic AA222 audiometer while otic capsule and auditory ossicles density were measured using Toshiba Aquilion 128 CT.
Results: Hearing loss was found in 22 of 36 osteoporosis patients ears (61.11%) and 8 of 36 non-osteoporosis patients ears (22.22%). The density of malleus, incus, ROI I, and ROI II between the osteoporosis and non osteoporosis groups showed significant differences (p<0.05; malleus: 1147 Â± 85 HU vs 1212 Â± 80 HU; incus: 1127 Â± 94 HU vs 1184 Â± 81 HU; ROI I: 1895 Â± 72 HU vs 1981 Â± 101 HU; ROI II: 1903 Â± 61 HU vs 1968 Â± 88 HU).). While for stapes density (1086 Â± 90 HU vs 1110 Â± 86 HU) did not show a significant difference (p>0.05). The hearing threshold between two groups (30.83 Â± 9.42 dB vs 23.26 Â± 8.09 dB) showed significant differences (p<0.05). The density of malleus, incus, stapes, ROI I, and ROI II negatively significant (p<0.05) correlated to the hearing threshold with each correlation coefficient were -0.498, -0.391, -0.255, -0.690, and -0.562.
Conclusion: The density of malleus, incus, and otic capsule between the osteoporosis and non-osteoporosis groups showed significant differences. The density of the otic capsule and auditory ossicles are negatively correlated with the hearing threshold.