Background: There are several approaches to solve the problems of many pathological processesâ€™ correction, such as clinical pathology and experiment in modern science. At the same time, genetically-conditioned diseases usually demand researchersâ€™ attention and generalization of earlier information for making the correction foundation of their manifestations in the future. Downâ€™s syndrome is considered to be one. Our objective was to review existing literature regarding physiological and morphological peculiarities of children with Downâ€™s syndrome.
Methods: A total of 30 relevant literature were reviewed regarding physiological and morphological peculiarities of children with Downâ€™s syndrome. The data collection for eligible articles were conducted from 1989-2017. Different database and manual search methods were used to find the topic-related articles.
Results: Abnormalities of heart, gastrointestinal tract and the system of urinary excretion are considered as the underlying congenital abnormalities for children with Downâ€™s syndrome influencing their lifespan. People with Downâ€™s syndrome have difficulties in their cognitive activity, such as lag in development, speaking, and reading. Limitation existence of ideas and scarcity of conclusions make studying different school subjects impossible for children with Downâ€™s syndrome. They need more time to master new skills and remembering new material. On the other hand, children with Downâ€™s syndrome possess positive personal qualities: they are tender, friendly and even-tempered. Conclusion: Downâ€™s syndrome is considered as one of the most common genetic diseases occurred newborns. Children with Downâ€™s syndrome have several physical abnormalities. It is important to understand children with Downâ€™s syndrome as a whole, as they can be put into a well-adjusted system of rehabilitation.