Skip to main content Skip to main navigation menu Skip to site footer

Physiological and morphological peculiarities of children with Down’s syndrome: A brief review



Abstract

Background: There are several approaches to solve the problems of many pathological processes’ correction, such as clinical pathology and experiment in modern science. At the same time, genetically-conditioned diseases usually demand researchers’ attention and generalization of earlier information for making the correction foundation of their manifestations in the future. Down’s syndrome is considered to be one. Our objective was to review existing literature regarding physiological and morphological peculiarities of children with Down’s syndrome.

Methods: A total of 30 relevant literature were reviewed regarding physiological and morphological peculiarities of children with Down’s syndrome. The data collection for eligible articles were conducted from 1989-2017. Different database and manual search methods were used to find the topic-related articles.

Results: Abnormalities of heart, gastrointestinal tract and the system of urinary excretion are considered as the underlying congenital abnormalities for children with Down’s syndrome influencing their lifespan. People with Down’s syndrome have difficulties in their cognitive activity, such as lag in development, speaking, and reading. Limitation existence of ideas and scarcity of conclusions make studying different school subjects impossible for children with Down’s syndrome. They need more time to master new skills and remembering new material. On the other hand, children with Down’s syndrome possess positive personal qualities: they are tender, friendly and even-tempered. Conclusion: Down’s syndrome is considered as one of the most common genetic diseases occurred newborns. Children with Down’s syndrome have several physical abnormalities. It is important to understand children with Down’s syndrome as a whole, as they can be put into a well-adjusted system of rehabilitation.

Keywords: Down’s syndrome children trisomy 21 morphological and functional disorders

References

  1. Skoryatina IA, Zavalishina S. Ability to aggregation of basic regular blood elements of patients with hypertension anddyslipidemia receiving non-medication andsimvastatin. Bali Medical Journal. 2017;6(3):514-520.
  2. Kotova OV, Zavalishina SYu, Makurina ON, Kiperman YaV, Savchenko AP. Impact estimation of long regular exercise on hemostasis and blood rheological features of patients with incipient hypertension. Bali Medical Journal.2017; 6(3):514-520.
  3. Zavalishina SYu, Vatnikov YuA, Kulikov EV, Yagnikov SA, Karamyan AS. Diagnostics of erythrocytes’ microrheological features and early abnormalities of rats in the model of experimental hypertension development. Bali Medical Journal. 2017;6(3):470–475.
  4. Vatnikov YuA, Zavalishina SYu, Kulikov EV, Vilkovysky IF, Nikishov AA. Correctional abilities of regular muscle activity in relation to erythrocytes’ microrheological features of rats with experimentally developed hypertension. Bali Medical Journal. 2017;6(3):449–456.
  5. Vatnikov YuA, Zavalishina SYu, Pliushchikov VG, Kuznetsov VI, Seleznev SB. Early-changes diagnostics of erythrocytes microrheological features in the model of dyslipidemia development in rats at the late stages of ontogenesis. Bali Medical Journal. 2017; 6(1): 216–222.
  6. Bikbulatova AA, Karplyuk AA, Tarasenko OV. Model of Activities of the Resource Training Center of the Russian State Social University in Terms of Professional Orientation and Employment of Persons with Disabilities. Psikhologicheskaya nauka i obrazovanie. 2017; 22(1):26–33.
  7. Bikbulatova AA, Pochinok NB. Professional Skills Competitions for People with Disabilities as a Mechanism for Career Guidance and Promotion of Employment in People with Special Needs. Psikhologicheskaya nauka i obrazovanie. 2017;22(1):81–87.
  8. Zavalishina S.Yu. Hemostatic activity of a vascular wall at newborn calfs //Russian Agricultural Sciences. 2012; 1 : 37-39.
  9. Zavalishina SYu., Nagibina EV. Dynamics of microrheology characteristics of erythrocyte in children 7-8 years with scoliosis with therapeutic physical training and massage. Technologies of Living Systems. 2012;9(4):29–34.
  10. Zavalishina SYu. Dynamics of hemostasis system at newborn calves with iron defiviency by use ferroglucin and glicopin. Zootekhniya. 2012;7:14–16.
  11. Nagornaya NV, Bordugova EV, Usenko NA. Dr. Down. The health of the child. 2013; 6(49): 159–162.
  12. Alexander G.E., Saunders A.M., Szczepanik J. Relation of age and apolipoprotein E to cognitive function In Down syndrome adults. Neuroreport. 1997;8(8):1835–1840.
  13. Semenova NA. The health status of children with down syndrome: dissertation ... of candidate of medical Sciences. Moscow, 2014;84.
  14. Esipova TP, Kobyakov EA, Markovska AV. Integrated development of children with down syndrome an early age. Novosibirsk: GOOI "Society "Down Syndrome", 2015; 34.
  15. Makhov AS, Zubenko MB. Physical culture and sport system for children with Down syndrome: design issues. Theory and Practice of Physical Culture. 2017;4:3.
  16. Mikhaylova IV, Shmeleva SV, Makhov AS. Adaptive chess educational technology for disabled children. Theory and Practice of Physical Culture. 2015;7:12.
  17. Kozlova SI, Demikova NS. Hereditary syndromes and medical-genetic counseling. Moscow, 2007; 290–291.
  18. Babayan VV. Clinico-functional and metabolic characteristics of children with Down syndrome: the dissertation of the candidate of medical sciences. Moscow, 2013. 142.
  19. Barashneva YuI. Down Syndrome. Medico-genetic and socio-psychological portrait. Moscow: "Triad-X", 2011. 12.
  20. Pueschel SM. Clinical aspects of Down syndrome from infancy to adulthood. Issues Law Med. 1989;5(1):87–99.
  21. Ranke MB. Disease specific growth charts, do we need them? ActaPaediatr Scand Suppl. 1989;356:17–25.
  22. Freeman SB, Torfs CA, Romitti MH. Congenital gastrointestinal defects in Down syndrome: a report from the Atlanta and National Down Syndrome Projects. Clin Genet. 2009;75:180–184.
  23. Chubarova AI, Semenova NA, Rumyantseva VA Pathology of the thyroid gland in children with Down syndrome. Experience of foreign countries. Down Syndrome. XXI Century. 2010; 2 (5): 9-12.
  24. Chubarova AI, Semenova NA Orthopedic disorders. Down Syndrome. XXI Century. 2011; 2 (7):9–11.
  25. Alekhina AV. Features of mental development of children with Down syndrome: author's abstract. diss. Cand. honey. sciences. St. Petersburg, 2000;22.
  26. Zhijanova PL, Field EV, Nechaeva TN. The formation of basic motor skills in children with down syndrome. Charity Fund "downside Up". Moscow, 2010;112.
  27. Mateescu LG. New approaches to problem-targeted education for families with a disabled child with down syndrome, as one of the methods to improve the quality of rehabilitation: dissertation... of candidate of medical Sciences. Samara, 2005;192.
  28. Goriyanova AV, Semenova NA Assessment of the rates of psychomotor development in children with Down's syndrome. Bulletin of the Russian State Medical University. 2013;1: 311.
  29. Zavalishina SYu. Activity of a vascular hemostasis at calfs of a dairy food. Russian Agricultural Sciences. 2012;4:49–51.
  30. Zavalishina SYu. Vascular hemostasis at calves in milk-and-vegetable phase of feeding. Zootekhniya. 2012;2:21.

How to Cite

Makhov, A., & Medvedev, I. N. (2020). Physiological and morphological peculiarities of children with Down’s syndrome: A brief review. Bali Medical Journal, 9(1), 51–54. https://doi.org/10.15562/bmj.v9i1.1099
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver
Download Citation
Endnote/Zotero/Mendeley (RIS) BibTeX

HTML
3

Total
3

Share

Search Panel

A.S. Makhov
Google Scholar
Pubmed
BMJ Journal

Ilya Nikolayevich Medvedev
Google Scholar
Pubmed
BMJ Journal